|
About the Constraint category
|
|
0
|
224
|
June 28, 2023
|
|
Missing Constraint Metrics (v4.1) for specific genes (e.g., ACE2 - ENSG00000159640)
|
|
2
|
21
|
January 28, 2026
|
|
Mutation rate table
|
|
1
|
96
|
November 21, 2025
|
|
Regional Missense Constraint
|
|
1
|
66
|
August 5, 2025
|
|
pLoF variants for gnomAD v.4
|
|
2
|
129
|
July 3, 2025
|
|
Gnoamd constrain v4 header. lof het/hom
|
|
2
|
389
|
April 28, 2025
|
|
Discordant variant observations between v2.1.1 and v4.1
|
|
2
|
81
|
April 7, 2025
|
|
How to obtain constraint per base?
|
|
0
|
53
|
January 29, 2025
|
|
pLoF Metrics by Gene TSV columns
|
|
3
|
112
|
December 11, 2024
|
|
GnomAD v2.1.1 Regional missense constraint file is incomplete
|
|
1
|
71
|
December 3, 2024
|
|
Comparing constraint between different population sizes
|
|
0
|
57
|
October 1, 2024
|
|
Number of observed variants vs hail query (v4.1.0)
|
|
3
|
162
|
September 7, 2024
|
|
Incomplete genomic constraint files v3
|
|
1
|
204
|
June 11, 2024
|
|
Large difference in pLI from v2.1.1 to v4.1.0
|
|
4
|
403
|
June 7, 2024
|
|
Constraint in TTN and high synonymous Z-score
|
|
2
|
387
|
May 30, 2024
|
|
How are the context-dependent mutation rates calculated for constraint modelling?
|
|
2
|
323
|
December 15, 2023
|
|
Discordant variant counts between the constraint metrics file and the browser
|
|
4
|
410
|
December 5, 2023
|
|
Chromosome X Constraint - V4
|
|
1
|
310
|
November 28, 2023
|