Constraint
| Topic | Replies | Views | Activity | |
|---|---|---|---|---|
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About the Constraint category
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0 | 205 | June 28, 2023 |
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GnomAD v2.1.1 Regional missense constraint file is incomplete
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1 | 12 | December 3, 2024 |
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pLoF Metrics by Gene TSV columns
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2 | 18 | November 27, 2024 |
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Comparing constraint between different population sizes
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0 | 19 | October 1, 2024 |
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Number of observed variants vs hail query (v4.1.0)
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3 | 60 | September 7, 2024 |
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Mutation rate table
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0 | 34 | July 25, 2024 |
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Incomplete genomic constraint files v3
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1 | 177 | June 11, 2024 |
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Large difference in pLI from v2.1.1 to v4.1.0
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4 | 196 | June 7, 2024 |
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Constraint in TTN and high synonymous Z-score
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2 | 219 | May 30, 2024 |
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How are the context-dependent mutation rates calculated for constraint modelling?
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2 | 258 | December 15, 2023 |
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Discordant variant counts between the constraint metrics file and the browser
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4 | 323 | December 5, 2023 |
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Chromosome X Constraint - V4
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1 | 255 | November 28, 2023 |
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Gnoamd constrain v4 header. lof het/hom
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1 | 291 | November 14, 2023 |