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About the Constraint category
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0
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227
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June 28, 2023
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Missing Constraint Metrics (v4.1) for specific genes (e.g., ACE2 - ENSG00000159640)
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2
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24
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January 28, 2026
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Mutation rate table
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1
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101
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November 21, 2025
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Regional Missense Constraint
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1
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71
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August 5, 2025
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pLoF variants for gnomAD v.4
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2
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136
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July 3, 2025
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Gnoamd constrain v4 header. lof het/hom
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2
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398
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April 28, 2025
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Discordant variant observations between v2.1.1 and v4.1
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2
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84
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April 7, 2025
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How to obtain constraint per base?
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0
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54
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January 29, 2025
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pLoF Metrics by Gene TSV columns
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3
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113
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December 11, 2024
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GnomAD v2.1.1 Regional missense constraint file is incomplete
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1
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71
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December 3, 2024
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Comparing constraint between different population sizes
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0
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59
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October 1, 2024
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Number of observed variants vs hail query (v4.1.0)
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3
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163
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September 7, 2024
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Incomplete genomic constraint files v3
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1
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206
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June 11, 2024
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Large difference in pLI from v2.1.1 to v4.1.0
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4
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413
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June 7, 2024
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Constraint in TTN and high synonymous Z-score
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2
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392
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May 30, 2024
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How are the context-dependent mutation rates calculated for constraint modelling?
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2
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324
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December 15, 2023
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Discordant variant counts between the constraint metrics file and the browser
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4
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410
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December 5, 2023
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Chromosome X Constraint - V4
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1
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310
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November 28, 2023
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