Dear Katherine Chao / gnomAD Production Team, In gnomAD v4.0 | gnomAD browser it is stated that “62,901,592 SNVs and 6,189,261 indels pass all filters in the v4 release.”. On trying to reproduce this number we arrive at 600,294,364 SNVs that pass all filters (out of a total of 786,500,648 SNVs lis…

Hello, my name is Daniel Marten and I’m a member of the gnomAD Production Team: 1 - One thing to note is that parts of the blog post you linked, including that Variant QC number you’re citing, only covers the gnomAD v4 Exomes Release. This is discussed under the ‘Creating gnomAD v4’ section , linke…

Variant QC SNV pass count v4

General

Qin October 28, 2024, 2:52pm 8

@dennishendriksen A joint (exomes + genomes) release is available from gnomAD v4.1, you may not need to merge them on your own, the vcf FILTER is also combined as explained here.

Topic		Replies	Views
The list of variants with incorrect allele frequencies in gnomAD-v4 General	2	305	May 6, 2024
V4: Number of missense variants in VCFs doesn't match the stats General	1	47	July 23, 2024
Discordant variant counts between the constraint metrics file and the browser Constraint	4	340	December 5, 2023
Quality score in gnomAD SVs v4.1.0 Structural Variation	1	25	December 18, 2024
gnomAD v4 genome and exome sample counts per genetic ancestry groups General	4	189	May 16, 2024

Variant QC SNV pass count v4

Related topics