Hello - Regarding the F508del variant, the European (non-Finnish) population in v4 has 49 homozygotes, while v4-nonUKB, which has a much smaller sample size, has 47 homozygotes. I’m unsure why the UKB samples had fewer homozygotes. Is this expected? Thanks!
| Genetic Ancestry Group | Allele Count | Allele Number | Number of Homozygotes | Allele Frequency |
|---|---|---|---|---|
| European (non-Finnish) | 17610 | 1178514 | 49 | 0.01494 |
|Genetic Ancestry Group|Allele Count|Allele Number|Number of Homozygotes|Allele Frequency|
|European (non-Finnish)|5465|417886|47|0.01308|