Hello all! For the gnomAD v4 Hail Table, the freq row field contains the index for all exomes that are adjusted (adj) or raw. Can I please know the difference between these two values?
Thank you very much!
Hello all! For the gnomAD v4 Hail Table, the freq row field contains the index for all exomes that are adjusted (adj) or raw. Can I please know the difference between these two values?
Thank you very much!
“adj” refers to allele frequency information after filtering to only high quality genotypes, which we define as:
GQ>=20
DP>=10 (5 for haploid genotypes on sex chromosomes)
allele balance >= 0.2 for heterozygotes
Regards,
Kristen