# Browser **URL:** https://discuss.gnomad.broadinstitute.org/c/browser/5.md [Latest](https://discuss.gnomad.broadinstitute.org/latest.md) · [Categories](https://discuss.gnomad.broadinstitute.org/categories.md) · [Tags](https://discuss.gnomad.broadinstitute.org/tags.md) --- ## [About the Browser category](https://discuss.gnomad.broadinstitute.org/t/about-the-browser-category/11)
**Author:** [@kchao](https://discuss.gnomad.broadinstitute.org/u/kchao)\ **Replies:** 0
Have questions about using the gnomAD browser or using its code? Ask them here! If you’ve encountered a bug, please make sure to report it in the gnomAD browser Github repository. For concerns about data or how it’s di… --- ## [BRCA1 gene page fails to load tonight](https://discuss.gnomad.broadinstitute.org/t/brca1-gene-page-fails-to-load-tonight/852)
**Author:** [@Susan\_WL](https://discuss.gnomad.broadinstitute.org/u/Susan_WL)\ **Replies:** 3\ **Last updated:** [September 10, 2026, 6:03pm UTC](https://discuss.gnomad.broadinstitute.org/t/brca1-gene-page-fails-to-load-tonight/852 "2026-09-10T18:03:21Z")
Tonight the BRCA1 gene page will not load for me. I have tried repeatedly over the course of the evening and it fails every time, showing only the message “Unable to load gene.” What fails: Direct URL: gnomAD Same URL… --- ## [Bug affecting transcript display in gnomAD v2.1.1](https://discuss.gnomad.broadinstitute.org/t/bug-affecting-transcript-display-in-gnomad-v2-1-1/810)
**Author:** [@audreykoneill](https://discuss.gnomad.broadinstitute.org/u/audreykoneill)\ **Replies:** 2\ **Last updated:** [April 1, 2026, 3:43pm UTC](https://discuss.gnomad.broadinstitute.org/t/bug-affecting-transcript-display-in-gnomad-v2-1-1/810 "2026-04-01T15:43:52Z")
Description: Cannot access transcript display in gnomAD v2.1.1. This applies to multiple genes. This is affecting numerous people in my organization. Error message: Cannot read properties of undefined (reading ‘tissue’) … --- ## [403 error using API via python gql](https://discuss.gnomad.broadinstitute.org/t/403-error-using-api-via-python-gql/807)
**Author:** [@malcolm](https://discuss.gnomad.broadinstitute.org/u/malcolm)\ **Replies:** 7\ **Last updated:** [March 12, 2026, 9:40pm UTC](https://discuss.gnomad.broadinstitute.org/t/403-error-using-api-via-python-gql/807 "2026-03-12T21:40:20Z")
Hi, a few weeks ago I used the API (through python) to access variant info for a number of genes. I’ve recently rerun the script for a new set of genes, but I get a 403 error from the server. I’ve tried again using the s… --- ## [gnomAD browser very slow](https://discuss.gnomad.broadinstitute.org/t/gnomad-browser-very-slow/801)
**Author:** [@Yasmin](https://discuss.gnomad.broadinstitute.org/u/Yasmin)\ **Replies:** 1\ **Last updated:** [February 19, 2026, 9:40pm UTC](https://discuss.gnomad.broadinstitute.org/t/gnomad-browser-very-slow/801 "2026-02-19T21:40:21Z")
Either get the message ‘unable to load variant’ or ‘service overload’ in the mornings (UK time). --- ## [Grpmax faf value in gnomAD VCF files](https://discuss.gnomad.broadinstitute.org/t/grpmax-faf-value-in-gnomad-vcf-files/759)
**Author:** [@yaarau](https://discuss.gnomad.broadinstitute.org/u/yaarau)\ **Replies:** 2\ **Last updated:** [September 10, 2025, 3:36pm UTC](https://discuss.gnomad.broadinstitute.org/t/grpmax-faf-value-in-gnomad-vcf-files/759 "2025-09-10T15:36:58Z")
There are new ACMG guidelines, and they include the use of FAF grpmax data from gnomAD (see: https://zifornd.com/blogs/how-acmg-guidelines-and-gnomad-are-aligning-to-simplify-variant-interpretation/). These guidelines re… --- ## [How to calculate hemizygous counts](https://discuss.gnomad.broadinstitute.org/t/how-to-calculate-hemizygous-counts/753)
**Author:** [@mirgin01](https://discuss.gnomad.broadinstitute.org/u/mirgin01)\ **Replies:** 2\ **Last updated:** [August 19, 2025, 7:11am UTC](https://discuss.gnomad.broadinstitute.org/t/how-to-calculate-hemizygous-counts/753 "2025-08-19T07:11:54Z")
Hello! I’m using Hail to build a pipeline that calculates allele frequency statistics by sex and ancestry. I’m aiming to replicate the gnomAD allele frequency table, which includes: Allele Count (AC) Allele Number… --- ## [Bug with structural variant browser](https://discuss.gnomad.broadinstitute.org/t/bug-with-structural-variant-browser/709)
**Author:** [@pujaltema](https://discuss.gnomad.broadinstitute.org/u/pujaltema)\ **Replies:** 2\ **Last updated:** [June 18, 2025, 4:19pm UTC](https://discuss.gnomad.broadinstitute.org/t/bug-with-structural-variant-browser/709 "2025-06-18T16:19:41Z")
Hello, The gnomAD SVs v4.1.0 browser does not work anymore (unable to load variant). Same when I use the dataset “gnomAD SVs” for a gene. Thank you for your help Kind regards --- ## [Wrong coordinates for the RNU4ATAC gene](https://discuss.gnomad.broadinstitute.org/t/wrong-coordinates-for-the-rnu4atac-gene/667)
**Author:** [@sylvie.mazoyer](https://discuss.gnomad.broadinstitute.org/u/sylvie.mazoyer)\ **Replies:** 2\ **Last updated:** [June 4, 2025, 12:48pm UTC](https://discuss.gnomad.broadinstitute.org/t/wrong-coordinates-for-the-rnu4atac-gene/667 "2025-06-04T12:48:10Z")
Hello, The RNU4ATAC gene is a non-coding gene responsible for three Mendelian diseases, therefore variant interpretation by diagnostic laboratories relies partly on the population data of gnomAD. For non-coding genes, … --- ## [Result table not showing](https://discuss.gnomad.broadinstitute.org/t/result-table-not-showing/637)
**Author:** [@michele.gentili](https://discuss.gnomad.broadinstitute.org/u/michele.gentili)\ **Replies:** 1\ **Last updated:** [April 16, 2025, 8:56pm UTC](https://discuss.gnomad.broadinstitute.org/t/result-table-not-showing/637 "2025-04-16T20:56:30Z")
Hi, result table is not working, I tried different queries. I’m using safari. The page is loaded, but the table is empty. “An error occurred, try reloading page or clearing filters.” --- ## [Liftover API from grch37 to grch38](https://discuss.gnomad.broadinstitute.org/t/liftover-api-from-grch37-to-grch38/549)
**Author:** [@Mileoniac](https://discuss.gnomad.broadinstitute.org/u/Mileoniac)\ **Replies:** 1\ **Last updated:** [February 4, 2025, 9:49pm UTC](https://discuss.gnomad.broadinstitute.org/t/liftover-api-from-grch37-to-grch38/549 "2025-02-04T21:49:09Z")
Hi, Is it possible to do liftover of a variant using the API? Is there a documentation on how to use graphql to construct queries? Thank you, Emiliano --- ## [gnomAD v.4.1 API?](https://discuss.gnomad.broadinstitute.org/t/gnomad-v-4-1-api/545)
**Author:** [@gruiz](https://discuss.gnomad.broadinstitute.org/u/gruiz)\ **Replies:** 1\ **Last updated:** [January 24, 2025, 2:59pm UTC](https://discuss.gnomad.broadinstitute.org/t/gnomad-v-4-1-api/545 "2025-01-24T14:59:03Z")
Hi, I recently learned about the allele frequency fixes in v4.1 and i wanted to download its data via API. Is there a way to do it? It seems only v2.1, v3 and v4 are available. I really appreciate your time. Thanks! --- ## [Different HGVSp of canonical transcript for ARHGEF18 (gnomAD v2.1.1)](https://discuss.gnomad.broadinstitute.org/t/different-hgvsp-of-canonical-transcript-for-arhgef18-gnomad-v2-1-1/527)
**Author:** [@bokbee](https://discuss.gnomad.broadinstitute.org/u/bokbee)\ **Replies:** 2\ **Last updated:** [January 10, 2025, 2:48am UTC](https://discuss.gnomad.broadinstitute.org/t/different-hgvsp-of-canonical-transcript-for-arhgef18-gnomad-v2-1-1/527 "2025-01-10T02:48:07Z")
When I searched for a variant (19-7509332-G-A) in gnomAD v2.1.1, I found that the canonical transcript’s HGVSp for this variant is p.Val347Ile. However, When I searched for the same variant on ClinVar again, the HGVSp o… --- ## [Access to Download](https://discuss.gnomad.broadinstitute.org/t/access-to-download/475)
**Author:** [@Imoleayo\_Opajobi](https://discuss.gnomad.broadinstitute.org/u/Imoleayo_Opajobi)\ **Replies:** 1\ **Last updated:** [October 16, 2024, 12:22pm UTC](https://discuss.gnomad.broadinstitute.org/t/access-to-download/475 "2024-10-16T12:22:55Z")
Good Day, Thank you for the great site. I would appreciate access to download on the sie, what do i need to do. Thank you. --- ## [All-sites allele numbers by ancestry group?](https://discuss.gnomad.broadinstitute.org/t/all-sites-allele-numbers-by-ancestry-group/469)
**Author:** [@calbors](https://discuss.gnomad.broadinstitute.org/u/calbors)\ **Replies:** 1\ **Last updated:** [October 10, 2024, 8:04pm UTC](https://discuss.gnomad.broadinstitute.org/t/all-sites-allele-numbers-by-ancestry-group/469 "2024-10-10T20:04:23Z")
Would it be possible for you to provide allele numbers for all sites for each separate ancestry group? I was only able to find the total count in your data. --- ## [Constraint metric](https://discuss.gnomad.broadinstitute.org/t/constraint-metric/429)
**Author:** [@MariAnn](https://discuss.gnomad.broadinstitute.org/u/MariAnn)\ **Replies:** 4\ **Last updated:** [September 11, 2024, 7:41am UTC](https://discuss.gnomad.broadinstitute.org/t/constraint-metric/429 "2024-09-11T07:41:05Z")
Why does the Lof observed not correlate with the number of LOF found in the gene? Example ASH1L In the constraint table: pLof, observed 18 and pLof score 1 However there are reported 60 LOF in ASH1L Main transcript. S… --- ## [Rounding the frequencies in the browser](https://discuss.gnomad.broadinstitute.org/t/rounding-the-frequencies-in-the-browser/431)
**Author:** [@Christine\_Preston](https://discuss.gnomad.broadinstitute.org/u/Christine_Preston)\ **Replies:** 3\ **Last updated:** [September 10, 2024, 2:53pm UTC](https://discuss.gnomad.broadinstitute.org/t/rounding-the-frequencies-in-the-browser/431 "2024-09-10T14:53:12Z")
Can you explain the rules for how many significant figures are displayed in the v4.1 UI? It seems to vary a bit, for example 0 is displayed as “0.000”, and often long values seem to be rounded at 7 or 8 values past the d… --- ## [Gene Symbols Starting with 'CA'](https://discuss.gnomad.broadinstitute.org/t/gene-symbols-starting-with-ca/442)
**Author:** [@summi](https://discuss.gnomad.broadinstitute.org/u/summi)\ **Replies:** 1\ **Last updated:** [September 4, 2024, 9:06pm UTC](https://discuss.gnomad.broadinstitute.org/t/gene-symbols-starting-with-ca/442 "2024-09-04T21:06:09Z")
Hello gnomAD Team, Quick question on searching gene symbols starting with ‘CA’ - such as CA11, CA10, etc. The results map to a variant, not the gene. Searching for the gene ID, eg ENSG00000063180, gets us to the corre… --- ## [Topic Loading chunk 595 failed.(missing: https://gnomad.broadinstitute.org/js/595-fc9ff4040fdf0d877f0b.js)](https://discuss.gnomad.broadinstitute.org/t/topic-loading-chunk-595-failed-missing-https-gnomad-broadinstitute-org-js-595-fc9ff4040fdf0d877f0b-js/419)
**Author:** [@Reinhold\_Innerhofer](https://discuss.gnomad.broadinstitute.org/u/Reinhold_Innerhofer)\ **Replies:** 1\ **Last updated:** [August 14, 2024, 3:44pm UTC](https://discuss.gnomad.broadinstitute.org/t/topic-loading-chunk-595-failed-missing-https-gnomad-broadinstitute-org-js-595-fc9ff4040fdf0d877f0b-js/419 "2024-08-14T15:44:59Z")
Description: i typed ldlr and pressed enter Error message: Loading chunk 595 failed. (missing: https://gnomad.broadinstitute.org/js/595-fc9ff4040fdf0d877f0b.js) Stack trace: ChunkLoadError at o.f.j (https://gnoma… --- ## [Assistance with Querying Non-Synonymous Variants for Specific Transcript ID](https://discuss.gnomad.broadinstitute.org/t/assistance-with-querying-non-synonymous-variants-for-specific-transcript-id/414)
**Author:** [@lucas\_chestnuttree](https://discuss.gnomad.broadinstitute.org/u/lucas_chestnuttree)\ **Replies:** 2\ **Last updated:** [August 9, 2024, 2:32pm UTC](https://discuss.gnomad.broadinstitute.org/t/assistance-with-querying-non-synonymous-variants-for-specific-transcript-id/414 "2024-08-09T14:32:26Z")
Dear gnomAD Team, I hope this message finds you well. I am currently working on a project that involves analyzing non-synonymous variations for specific transcript IDs. (i.e given a transcript ENST00000624687) I am int… --- ## [gnomAD v4.1 not working?](https://discuss.gnomad.broadinstitute.org/t/gnomad-v4-1-not-working/388)
**Author:** [@Helen\_Lord](https://discuss.gnomad.broadinstitute.org/u/Helen_Lord)\ **Replies:** 2\ **Last updated:** [July 19, 2024, 9:07pm UTC](https://discuss.gnomad.broadinstitute.org/t/gnomad-v4-1-not-working/388 "2024-07-19T21:07:42Z")
Hi, I can 't seem to look at any genes in gnomAD v4.1.0 this morning. I have tried several different browsers and several diffeent genes but it just says unable to get results. --- ## [Topic Cannot read properties of undefined (reading 'genes')](https://discuss.gnomad.broadinstitute.org/t/topic-cannot-read-properties-of-undefined-reading-genes/279)
**Author:** [@Anton\_Esibov](https://discuss.gnomad.broadinstitute.org/u/Anton_Esibov)\ **Replies:** 1\ **Last updated:** [May 1, 2024, 8:48pm UTC](https://discuss.gnomad.broadinstitute.org/t/topic-cannot-read-properties-of-undefined-reading-genes/279 "2024-05-01T20:48:33Z")
Description: I was trying to view all genes affected by large deletion in “Consequense” section Error message: Cannot read properties of undefined (reading ‘genes’) Stack trace: TypeError: Cannot read properties of un… --- ## [Error while switching between GRCh38 and GRCh37 and checking Non-Neuro MAF](https://discuss.gnomad.broadinstitute.org/t/error-while-switching-between-grch38-and-grch37-and-checking-non-neuro-maf/152)
**Author:** [@Oswaldo\_Lorenzo](https://discuss.gnomad.broadinstitute.org/u/Oswaldo_Lorenzo)\ **Replies:** 1\ **Last updated:** [February 1, 2024, 2:23pm UTC](https://discuss.gnomad.broadinstitute.org/t/error-while-switching-between-grch38-and-grch37-and-checking-non-neuro-maf/152 "2024-02-01T14:23:59Z")
Description: Switching between GRCh38 and GRCh37 for certain variants to check how do they lift over and checking MAF in Non-Neuro datasets Error message: Cannot read properties of null (reading ‘forEach’) Stack trace: … --- ## [Blocked when using API to get AF](https://discuss.gnomad.broadinstitute.org/t/blocked-when-using-api-to-get-af/149)
**Author:** [@yfarjoun](https://discuss.gnomad.broadinstitute.org/u/yfarjoun)\ **Replies:** 1\ **Last updated:** [February 2, 2024, 7:49pm UTC](https://discuss.gnomad.broadinstitute.org/t/blocked-when-using-api-to-get-af/149 "2024-02-02T19:49:19Z")
Hi, I’m trying to annotate a small (several hundred) dataset of variants. I’m using the API but after about 10 queries I seem to get blocked (I’m using gnomadR so I don’t see the error message). is there a way to submit… --- ## [Topic Cannot read properties of null (reading 'map')](https://discuss.gnomad.broadinstitute.org/t/topic-cannot-read-properties-of-null-reading-map/157)
**Author:** [@epinto](https://discuss.gnomad.broadinstitute.org/u/epinto)\ **Replies:** 1\ **Last updated:** [February 2, 2024, 4:23pm UTC](https://discuss.gnomad.broadinstitute.org/t/topic-cannot-read-properties-of-null-reading-map/157 "2024-02-02T16:23:07Z")
Description: Error message: Cannot read properties of null (reading ‘map’) Stack trace: TypeError: Cannot read properties of null (reading 'map') at T (https://gnomad.broadinstitute.org/js/507-64cb7d9b695f7f5238cd… --- ## [Access to preprocessing pipeline code](https://discuss.gnomad.broadinstitute.org/t/access-to-preprocessing-pipeline-code/109)
**Author:** [@iggy\_m](https://discuss.gnomad.broadinstitute.org/u/iggy_m)\ **Replies:** 3\ **Last updated:** [January 10, 2024, 2:28am UTC](https://discuss.gnomad.broadinstitute.org/t/access-to-preprocessing-pipeline-code/109 "2024-01-10T02:28:02Z")
Hi GnomAD team :wave: The GnomAD browser is really excellent. We would like to try to use the front-end to help visualise our own dataset (as it is not suitable for inclusion into the wider GnomAD data set). Can you ple… --- ## [Fix Gene page "export to CSV" genetic ancestry group data values](https://discuss.gnomad.broadinstitute.org/t/fix-gene-page-export-to-csv-genetic-ancestry-group-data-values/89)
**Author:** [@rhgrant](https://discuss.gnomad.broadinstitute.org/u/rhgrant)\ **Replies:** 0\ **Last updated:** [December 5, 2023, 9:26pm UTC](https://discuss.gnomad.broadinstitute.org/t/fix-gene-page-export-to-csv-genetic-ancestry-group-data-values/89 "2023-12-05T21:26:49Z")
On the gene page, users can download the information present in the variant table to a CSV file for local usage. With the release of v4, this CSV file contained faulty counts for AC, AN, AF, and Number of Homozygotes for…